Addiction is not a one‑size‑fits‑all illness. Each substance—whether alcohol, opioids, stimulants, or prescription medications—interacts with the brain and body in unique ways. Effective rehabilitation acknowledges that there are many different types of addiction, each requiring a tailored therapeutic approach to address its unique challenges. In this ≈750‑word article, we explore why customizing treatment plans to specific substance profiles enhances success and reduces relapse. Variations in Substance Effects and Withdrawal Different drugs produce distinct patterns of dependence and withdrawal: Understanding these differences guides choice of medications, therapy modalities, and aftercare. Customized Clinical Pathways The Role of Dual Diagnosis Many clients present with co‑occurring mental health disorders—depression, anxiety, or bipolar disorder. Treatment…